You can build up static without discharging it on your components. Anyway, using a vacuum isn't as unsafe as many would make you believe. Just make sure the nozzle doesn't make contact with the components and try to keep them grounded (by keeping the cable plugged in/regularly touching the case and nozzle).
Compressed air without a vacuum = dust in your face. You don't want that.
Or do as I do and use a compressor in the garage Careful for moisture (especially oil) though.