You bcan't run render scales abouve 100% with AA. If you change render scale abouve 100%, then AA is disabled. I'm running 200% render scale on a 2560x1440 monitor and I see NO jaggies at all on anything, and still get abouve 60FPS. Infact, i've locked my FPS to 65 via console and it very rarely dips. i7-4790K@4.4Ghz, gtx 1080@2Ghz