Originally Posted by
VigilantRose
As I see it, there are three central traits to the Holy Priest artifact weapon: Reverence, Power of the Naaru and Say Your Prayers. These are the traits you probably want to invest with relics, since they give the greatest return for their specific spells (5% to Heal/Flash Heal, 6% to Prayer of Healing or an exponentially increasing 6.2%+ to Prayer of Mending). Of these, Reverence is far more important for 5-man and Say Your Prayers is really a raid-only tactic.
On the other hand, there are some traits that you're taking only because you want to finish the weapon and get to the gooey center: Trust in the Light and Focus in the Light.
Serenity Now and Light of Tu'ure I look on as gilding the lily. Holy Priests are already exceptionally capable at burst healing single targets. Being able to heal someone for more than their maximum health with instants every 45 sec is nice, but hardly necessary.
Given the above, it seems a 'right hand' route is far more worthwhile. You pick up the talents you need first, first (Reverence before Say Your Prayers). You avoid the take-these-last talents like Trust in the Light and the overkill of Serenity Now and instead just focus on improving the heals you'll usefully cast.