Update
Yesterday was Raid Night for us, so didn't want to wipe everything just yet and fix it all back up before Raid. Following screenshots will show you what I changed and the results of those changes, I also turned Shadows down from High to Good for another 15-20 FPS gain.
Low FPS w/Settings
Better FPS w/Settings
The first thing I did was just completely disable all addons and compared it with the FPS I was getting with them all on standing in the same place, no difference, so turned them back on and started tweaking a few things. Changing these got me by for the night but I definitely do not believe the issue is resolved because normally those settings do not have to be scaled back.
Another thing I noticed after raid, so this is about 3.5-4hrs of my game running, is that my FPS dropped by the end of the Raid. I ported to Dalaran after Raid and was sitting somewhere around 50ish FPS. Exited the game and relaunched it..standing in the same place, boom..100+ FPS again. Memory leak?
This evening might be when I just delete all of those folders and rebuild the UI. Idk yet..