Originally Posted by
Luneward
I suppose my question would be: How often do you really serve as DPS for your raid? If not very often, I would suggest not really worrying about it, and possibly even swapping the trinket for something else. Once 5.4 hits, changes to our mastery is going to make Rune sub-optimal at best (Probably only slightly better than Talisman of Bloodlust is for us). If you still want to make use of it, I wouldn't make incredibly precise reforging of your mastery due to how often you are probably going to replace gear pieces. Not to mention Terror in the Mists can potentially mess with your Rune tuning since it will throw off the primary stat selection if it is procced when Rune activates.
Any trinket that can proc a secondary stat can potentially mess Rune up - unless it procs the same secondary stat you want Rune to activate with. Though I imagine a crit focused Rune proc wouldn't be a bad thing once 5.4 rolls out (save Energizing brew and a stack of 15 TeB for a proc and you have full energy regen, +90% damage, and 100% crit for 10 seconds). I still think it might be best not to even bother worrying about at this stage in 5.3 unless your guild wants you DPSing for heroic progression for some reason instead of healing.