The question isn't "Can humans know everything?" or even "What is knowledge?" The question refers to the possibility that what there is to be known is without limit.
Let's reduce knowledge, then, to simple arithmetic, just for the sake of argument. If we can prove that knowledge in this branch of, er, knowledge is infinite, then we can say that knowledge is certainly infinite if we take into account all the other areas of, er, knowledge.
So, arithmetic. The answer to the question, 1+1=? is something that is known. The answer to the question, 1+2=? is also known. However, numbers themselves are infinite, and 1+?=? is a simple sum that can be rewritten an infinite number of times.
If we take language, I can say, "How big is your big cat?" Then I can say, "How big is a cat that is bigger than your cat?" Then I can say, "How big is a big cat that is bigger than the big cat that is bigger than your cat?" Then I can say, "How big is the big cat that is bigger than the big cat that is bigger than the big cat that is bigger than your cat?" And so on.
From this we can see that knowledge is certainly infinite. But we can also see that it doesn't matter whether it's infinite or not, because what makes it infinite is the useless garbage that nobody needs to know about.
QED.