Once again: SimC has very high reaction time, exactly for things like missing a dot application. It's a exgaussian distribution with mean 650ms. I wouldn't call that "faster than a human", on the contrary.
Whydrood's Min/Max numbers are a great example of interpreting more than just the DPS number. In Simc you shouldn't use the min dps, but rather something like the 5% percentile ( to get a statistically more realiable comparison ). Comparing the variance of the DPS can be very important for high-end raiding guilds which depend on constant performance delievered. On the other hand, questioning such fundamentals as "hit is always best" is a good thing, to clearly understand the reasons for ones gear decisions.
The whole thing really is a good example showing how people usually just look at one single number, instead of taking a closer look at all the detailed statistics SimC provides. Really can't blame the program for that.