the art oc "clicking" is like playing a piano. After a while you just know where to move your mouse without looking. Helps to have a UI mod so you can rotate while you're down inside your hotbar clicking away that way you can avoid the "click-drag-move" motion. (used to do that, horrible when trying to battle and manage CDs at the correct time)
not so bad once you get used to it, been beating key binders 1v1 for yrs now. Used to beat ranked arena players on my server with pve gear back in wrath... then again, it helped being a ret paladin lol.