Yes, but those were generally right after a patch/raid was released and no one really knew the mechanics.
I can recall wiping multiple times on Ultraxion when tanks didn't know what to do and people refused to push their buttons (and on the trash before Ultraxion when people refused to taunt the drakes down), on Spine of Deathwing when people didn't realize you didn't need to roll him in LFR and attempted it which just resulted in everyone flying off, and on Garalon the first week it was released when people didn't understand crush or pheremones.
I remember those spine of deathwing days. It was pretty funny to see people not know what the mechanics of the roll were and just flew off.
Off topic: btw did you change your forum name?
It is my humble opinion that TBC was the most entertaining expansion.