In advance im mastery/crit warrior not like the other 98% population of prot warriors "avoiding" stuff.
Im a warrior i take stuff head on!
Personally i dont switch glyph's i got my 4 useful glyph,s and i switch TC with Rage for more "defensive" or "offensive" stile.
As for talents we dont have much room of a choice, but you can play with mass reflect in galakras fight, and narushen fight ( facing your fears! reflect, mass reflect,reflect and add is dead), and maybe mass spell reflect if your co-tank can handle execute without externals.
Mostly using BB and DR and switch those only for Nazgrim, becouse im pretty much left alone to control adds at <10% (thanks to banner) and using stuns and other fun stuff.
On siegcrafter i run with BB&DR as SB really disapointed me damage wise, SS, Tc and rage glyph's.
starting the fight, taking 3 stacks, taking add, lauching BB at safe distance from boss, when add lands or "about" to land, i jump on him and if im lucky i pretty much oneshot him with SS if it crit's, otherwise DR fallows afterwards. At 5stack's i kill add before he correctly "lands" and louches DFA.
When ill get back home ill think about stuff that maybe im using on other bosses ;>