Originally Posted by
Krisshaman
Mastery proc and echo proc can only happen once per cast, but which happens first and happens to which spell is uncontrolled, so an echo can overload, or an overload can echo, but an overload from an echo cant echo again, same the other way around.
And yes, it is possible for the multistrike trinket to allow 6 bursts to happen from one attack. I would buy a lottery ticket if that happened though.
Edit: The multistrike effect is called toxic power or something like that, so no actually, the max would be 3 ever.