Just adding - we're talking about the opener. So far best results i have netted are with Prep - SnD - Ambush - Rupture (should be at 5 CP now with HaT) - SB - Hemo - SD - then cycle as normal (after FW from SD has exprired, i throw Vanish).
Anyway, in the grand scheme of things, we're talking about a small damage increase. I personally have macroed SD with SB - if SB have something like 7 seconds left, i delay SD to align the two; the additional cp generation during SD means that you're basically doing Ambush/Evis for all SD duration.