It kind of hard to judge how much you do not know. I would imagine we know 1/10000000000000000000000000000 of knowable knowledge or less.There's a lot we don't know, but let's be realistic, there's not THAT much we don't know. I mean, we know a LOT of stuff, it's not like 1000 years ago when we didn't know where rain comes from. Scientific breakthroughs have been basically slowing down a lot. I mean, we've progressed stuff a whole bunch, sure. You can fit a camera, a calendar, a jukebox, a computer, a compass and a torch all inside a phone now, but our advancements are mostly evolutionary now, rather than revolutionary. Building the first plane, discovering antibiotics, combustion engines... this is stuff that like... changes stuff forever, for everyone. Completley revolutionises the world, lets new stuff that we never even dreamed of happen. A few hundred years ago this kind of stuff happens like from one year to the next... now you're lucky to hvae something happen in your lifetime, you know?
I know that's all like, tempting fate and like "oh well X years ago such-and-such said we'd never blah blah blah and now look" and like "the wisest people just know how little they know and ignorent people think they know everything" and stuff, but actually look at the advancements we've made and put them into evolutionary or revolutionary categories. Most recent ones have been evolutionary, and that's not enough to get interstellar travel. You can't just beef up a combustion engine or a rocket untill you get there.