Yeah I can be ok with implied knowledge, but I honestly didn't have clue what was going on. I wish someone shared some of that implied knowledge. All I knew there were some alien snake things that apparently make zombies, a young old man as a bad guy who i guess has a plan, a hot chick badguy who i guess has a different plan, and a robot that's...fuck it. I had no idea what David was about. Then there was something about religion, and something else about the missing link, and Charlize...damn did she look good in a space suit.
Everything else you said I am good with. It was gorgeous and had the perfect sci-fi feel to it. I said above it was like many scenes from different movies grafted together. Everyone of those scenes was great and implies a much greater movie...just not all mashed up into what Prometheus was.
And damn it Charlize...why didn't you just run to the side...you were way to hot to die stupidly!