If you literally mean sentience and not Sapience, its probably pretty likely, considering theres plenty of sentient life on Earth that isn't human.
If you mean sentience as in Sapience, then thats a tricky question. Its entirely possible we can encounter sapient life and never know it - life that is so different to what we understand or can conceive that any interaction is beyond the frame of human comprehension, thats the kind of thing the universe could end up throwing our way. I'd say that, with how vast the universe has to be there is likely something out there, probably many different forms of that something.
The real question is if humanity, if it survives long enough in universal terms, would be capable of realising anything thats simply too alien. Its not really a question of preference for me considering statistically the odds are in favour.