A good friend of mine who I find to be reasonably attractive, she would receive tons of messages, and A LOT of asshurt "Y U NOZ RITE BAK" messages.
I haven't really had a Online Dating profile in a long time (minus a short time not to long ago with one open and shut in under 48 hours because it was a waste of time due to lack of quality women on it) but I would get a number of women who wrote me first. I normally responded back and respectfully declined most of them because I wasn't interested, and received far fewer asshurt responses.
Based on that and a few other people I know, my personal opinion is that most overly sensitive women have a horrible time with it. Most women who can just say... "effing douche bag /block" probably have a much better time then most men.
With that said unattractive women will have a much easier time then unattractive men just due to the fact that men seem to out number women on them a far bit.