Alright but then what's up with Nova being relatively high prio on two targets?
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This probably won't be as relevant for anyone in mythic gear, but I wanted to see how certain trinket combinations scaled to know when I would be replacing Coin, and when/if I should pick up Alchemy.
-667 ilevel profile
-EM/PE/LM
-5 min patchwek
-Not taking into account 6.1 changes
-only simmed up through heroic BRF
-didn't bother simming the crit trinket, but it may be worth it
So right away, Stone is a BiS item until at least mythic BRF. But since 6.1 is coming after BRF opens, it may not matter as much. H_Dragonspine combines well with Coin, then better with N_Beating Heart, then better with M_Scales. And H_Dragonspine/H_Beating Heart beats out many of the alchemy combos.
For non-mythic raiders it looks like Stone of Fire is about as solid an option out there if you have the patience for 6.1, and if not then Heroic DS/BH.