Originally Posted by
Crisius
Yes. An alternative is to /cast [@focus] after setting something as a focus, but it's more work and requires a separate keybind to set stuff as focus, something you'll likely need to use a mouseover for anyway.
Another thing to mention about that macro he posted is that it'll cast pummel on your current target if there is no mouseover target. If you add [@mouseover,exists,harm] to it it'll make it even better, by only being eligible for mouseover interrupts if you're mouseovering a hostile target. (Mouseovering a friendly target, like another melee on Oregorger, and hitting the keybind will mess up your interrupt on the boss without the harm part)