You gotta shadow reflection and vendetta in your opener, research a good mut opener if need be.
You should vanish on cd to generate more combo points.
If you get a blindside proc, use it instantly. Don't ever mutilate if you have yet to cast your proc. You should only avoid using it if you have 5cp ready and no envenom up, in that case apply envenom and cast away.
Pool your energy in phases you know youll be doing more damage.
Lack of crit,4pc and trinket can mean you're starved for energy and combo points. So keep that in mind