As someone who has worked in pre-clinical studies with lab animals, the realistic result would be pretty disappointing. Nothing would happen.
The main reasons are:
1.) The lab rat/mouse populus is much less than 0.01% of the mouse/rat populus of earth.
2.) Even of those rats most don't have any meaningful mutations like exceptionally high intellect, etc.
The reasons why lab rats are kept genetically seperated from regular rats are to have a level testing field. This is also why researchers must approach lab animals with the utmost care because infecting them with any kind of virus/bacteria would contaminate the whole colony and render the results unusable.
Also many people have a wrong idea about animal tests. Most animal tests (at least nowadays) are tests that cannot be performed on humans. Testing cremes and low risk medication is just done on humans directly.
In a regular animal test a serious condition is induced in the healthy animal (mechanically or chemically) for example a stroke, heart failure, liver failure, COPD, etc. Then medication or surgical procedures are tested to reverse the condition. This has generally no effect on their DNA or anything that could be considered a "mutation".