NAS HDD - NAS Optimized or Not?

[Forgettable]

So I'm going to putting together my first every NAS system this weekend. My question is simple:

Is it required to install a hard drive that is "NAS Optimized" in the NAS system? Or will a standard hard drive work?

Bonus question: What are the ACTUAL benefits of a NAS optimized hard drive over a standard one for your average Joe who just wants to be able to sync files/pictures/movies between all connected devices? (ie: Not what the manufacturer's claims as silly benefits)

[chaud]

Standard drives are okay for most use cases, but if the price difference is small there isn't any reason not to go with most of the NAS drives. Small tweaks / component changes that might help the drive live longer and perform better. Some okay reading on it here: http://www.storagereview.com/pick_th...s_desktop_hdds