Originally Posted by
Skozen
Reaper's Harvest is good sometimes because a full-stack Necrotic Plague hits really hard on AoE. The main disease component of virulent plague seems much weaker than necrotic plague so the wandering plagues generated will be unimpressive. The good damage from virulent plague comes from when it explodes or when the target dies, which has no interaction with Reaper's Harvest which only procs off of the normal ticks (supposedly.) Now, if the explosions can proc off the wandering plague it might be worth equipping for AoE because that will greatly increase the number of explosions.