I'm a bit confused by talent choices. I've read through various guides in various places, like IV and LOSS, and I can't see a clear consensus on a few things.
One is the choice between Soul Conduit and Siphon Life. I've seen either recommended for multiple resp. single target, and now I don't know if it's typos, bad advice from someone, or just too close too call. My guess would be that SC is better for multiple targets because you tend to spend more shards there (more Agony ticks)? I don't trust SimCraft results at my low gear level, as it's so unoptimized there could be any number of distortion effects at play.
Another question concerns a legendary, Lethtendris' Power Cord when using Contagion - should I time UA re-applications so that they don't overlap, to give it a chance to proc? Or is it not worth the risk of increased downtime on Contagion?