Well it looks fairly good to me, it would definetly work for what you have to do.
Death Rune Mastery, I'm not totally sure is worth it. Honestly I would rather use more Obliterates that have 2 death runes for more Heart Strikes. And the only reason I would ever use Death Strike while raiding is to keep myself above the 75% threshold for Blood Gorged.
Vampiric Blood seems like just a waste of a talent point. Blood knights aren't too good for tanking in the first place, and I don't know what you would do with this spell as a dps, other than use it to give a small uneeded boost to your utility.
Blood-Caked Blade, just wow, see; I plan to do the same thing as you and go dps blood as an end game raider, and I keep debating myself on getting this talent or not. It seems like a mini Seal of Command, I just don't like that its a 15% chance proc rate and would only give a slight boost to your overall dps, unless you got extremely lucky and it proced a lot. But my preference is to have my dps controllable, and not wild, basing it off chances and procs. It could end up messing you up by not procing often enough, and basically wasting 3 talent points. But if this talent floats your boat, it boosts your overall damage, so go for it, after all I'm not even sure if I won't take it yet.
Everything else looks good and in the right spot though. This is, at the moment, the build I plan to use for this sort of stuff, if you want to compare and contrast or anything.
http://talent.mmo-champion.com/?deat...00000000000000