With the introduction of some new and incredible talents in both the Balance and Restoration trees, the options for how to spec and play a Resto Druid are now varied and based on one's own preferences and play-style.
The following spec is the one I will most likely go with in the expansion:
Heavy HoT Healing
This spec takes full advantage of the reduced GCDs and increased durations of Lifebloom and Rejuvenation and of the increased crit-chance of Regrowth, as well as the several talents that add other effects or increase the healing coefficients of these spells (including those in the Balance tree) and Flourish. Nourish will be a secondary heal with this spec, but will be the primary direct-healing spell outside of Regrowth (HT won't even be an option unless used in a NS-HT combo). Likewise, Tranquility will remain a fairly useless AoE healing spell as Flourish will easily surpass it in versitility (it can heal any group within a raid and it does not have to be channeled and has no CD). I chose to take 1/3 in Natural Perfection and 3/3 in Living Spirit and Splendor, but these points can be rearanged depending on one's preferences. Mana conservation will be almost a non-issue with the many talents that increase mana regeneration or decrease the cost of the healing spells (coupled with the fact that healing spells like Lifebloom will no longer spammed whenever the GCD is up, allowing more time between casts and taking more advantage of the "5 second rule"). This spec would benefit well from Glyphs like Glyph of Lifebloom, Glyph of Rejuvenation, and Glyph of Regrowth. (Glyph of Innervate is a secondary option but may prove to not be necessary with the improved mana efficiency of this spec.)