Hi,
I have always used my 1 to = and F1 to F12 for my keybindings, and this has worked for all my characters so far.
For my shaman i also use Z for Lightning bolt and X for Chain Lightning since they are easy to hit by my thumb.
When FS was added back to the rotation i was beginning to run out of keys i could reach and now fire nova plus fire elemental i have hit a wall. I just don't have enough fingers / keys
My main abilities used regularly are stored on 1 to 4 plus f1 to f3 i think, since they are easy to reach
I am interested to know how you guys set it up, because right now i can't keep up with the rotation. Just too many bleeding buttons to hit.