Originally Posted by
Fry-Lock
All these "boss favors x spec" crap doesn't matter, because the real question is what are you better at? If you're ok at affliction, but kick ass as destro, you're probably gonna do better as destro. If you're good enough at affliction to kick ass, then you will probably lose DPS by going destro. It's as simple as that.
Affliction kicks ass if you execute a perfect rotation, but if you mess up a few times, it loses it's advantage. Personally, I'm not very good at it. I just got too frustrated learning affliction, and the new fights in ICC at the same time.