If you could be 100% sure that the sequel would be at least as good as the original part, what games would you like to see?
For me it would be:
Sacrifice: Great game, which I just packed out again recently. very innovative gameplay, with an interesting story premisse. Sadly was a flop on markets, because it probably was too over the top for the general playerbase.
Giants: Citizen Kabuto: I have never laughed as much in a game as I have with this one. The game itself is good. It's not pure genius, but it was fun to play (especially the rts part). Also sold rather poorly
Vampire: The Masquerade: Bloodlines. Kind of like Mass Effect or Dragon Age, this was one of the first games which gave you pretty much total control over the story. And it has a gigantic replay value, because every clan (read class) plays very different. I'd love to see a game like this in the Requiem setting.
and maybe Psychonauts. Simply awesome humor.