Be careful though, as these client-side macros external to the WoW client may violate your Terms of Service.
Edit: There are two ways that you can use the Lightwell with just clicking one button, the first is the well-known one where you hover your cursor over the shiny yellow object on the screen and press the right-clicky button on your mouse. You could try to position the cursor over the shiny object and then leave it there while you smash your IWIN button so you could just hit the right click on the mouse if you needed heals but the problem with that is if you have to move or if another player stands between you and the object your cursor is no longer positioned properly, and if someone in on top of the thing you may have to run around the room trying to find that perfect angle which will allow you to see and right-click the Lightwell. The second method does at the very least resolve this problem, but it is a trade-off solution. But in some cases it may be worth it. If you want to be able to use the Lightwell without any interruption to your dps and also be able to move and use it, all with one click, here is what you have to do:
1. Focus the Lightwell
2. Hover your mouse over the focus frame (focus frame can be moved anywhere on the screen and will never be obstructed by in game objects, you can keyboard move/strafe all you want and the cursor will still be hovering over the focus frame)
3. Have a keybind set for "Interact with Mouseover"
4. Whenever you need a heal press the button