Not sure if it has been mentioned already, but The Bucket List really got to me. Of course Up, Toy Story 3, The Lion King are all good ones that bring a tear to the eye too. Heck, I even get a lump in my throat watching Beauty and the Beast. Damn you Disney/Pixar!
I found In Bruges to be quite emotional at points too.
Thinking about it, I was a bit misty eyed watching Kill Bill vol. 2 as well, when
*BIG FAT SPOILER*
she is reunited with her daughter.
I think I must be a softy at heart?