I ALMOST forgot there was a game on. Too busy playing Kobolds and Catacombs. I'm here now though, so this better be good or I'm back to playing Dungeon runs.
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If the circumstances for the game are not okay (people not able to get safely to the game or back, too much smoke in the air to be outdoors, anything that would prevent the game being played in LA this week-end will mean the game location will likely get moved to somewhere else where the game CAN be played this week-end. It is exceedingly rare for the NFL to not play a game and move it.
The only time that's happened to my knowledge is this year when the first week of the season the Dolphins and Bucs decided to move their game to a later date due to Hurricane danger. That game got moved to the week both teams had their bye.
This late in the season though there's no bye weeks and every game HAS to be played between now and January first. I strongly suspect the NFL would shift the game elsewhere this week-end and made sure it was played.