I was running aff with AC / PS, and you have an absurd amount of damage from 110 -> 116 (especially with current 965+ ilvl). Everything is instant cast, and PS basically heals you for whatever you end up getting chunked for on HP. I started finally using blueberry around 115 (things start to hit a bit harder) and it was fine.
After the slow ring stops working you basically have to start running as Destro, Aff just doesn't deal the damage after this point. I've found destro much better than demo just because you can burst things down much quicker. Demo is like a water drip that you slowly turn on, where as destro actually has the burst.