Good models should have variables that are changeable, so that the model reflects real time. Models are not ever meant to say 'This WILL happen", only "This will likely happen based on these current variables". If something changes, then the model needs to be adjusted. If the virus has shown to be evolvable, then that needs to be included.
Frankly, I just dont think you understand how proper modeling, and problem solving, work in general because you are considerably misunderstanding what modeling is, and what the purpose is.