Mega-Thread: Coronavirus Pandemic

[Masark]

Well, vaccine shedding is a real thing, but for Polio-vaccines

Only the live-virus oral polio vaccine. Which hasn't been used in the USA for over 20 years.

[Forogil]

Only the live-virus oral polio vaccine. Which hasn't been used in the USA for over 20 years.

True, but it's still used elsewhere, and in recent years the polio-vaccine has been causing most of the reported polio-cases worldwide.

For the US the only odd part is that it took so long to switch.

[Gaidax]

Word is that vaccinations for 6-12yo will start around December once approval is granted.

[Ursus]

Ok, the school gives itself the name "The Brain School". Should be "Lack-of-brains School".

"Shit-for-brains School" would also work.

[Rasulis]

Word is that vaccinations for 6-12yo will start around December once approval is granted.

It looks like we'll start vaccinating 5 - 11 years old starting November.

Meanwhile, rain, wind and fog here. It has been raining all day long. We biked to Ocean Beach this morning and there were people surfing the 30 - 50 feet waves. Category 5 atmospheric river and Cat 3 Hurricane winds. Good time to turn the fireplaces on and make tempura.

I guess the drought is over?

[PhaelixWW]

I guess the drought is over?

HahahaHAHAHAHAhahahaha... *sigh*

The drought in California only takes a break now and then.

Also, the last time the drought was "over" and then back again, it burned half the state to the ground.

[Rasulis]

HahahaHAHAHAHAhahahaha... *sigh*

The drought in California only takes a break now and then.

Also, the last time the drought was "over" and then back again, it burned half the state to the ground.

No one expect the drought and fire to go away forever. In California, a respite is the best that we can hope for. Drought and fire are part of living in California. Back in the early 90s we had a fire that burned the hillside behind our property in San Diego. We were watching the firefighters on the hill from our living room. In late 2000s, we were cleaning our house, which had been kept close for two years while we were in China, and the Witchcreek fires were burning along the hillside ridges surrounding our home. It was surreal. At night the sky above us was red. The power was out also. Also, October and November are usually our worst months for fire with the Santa Ana and Diablo winds. So the early rain is a welcome change. The reservoirs definitely can use the water.

Back to showcasing San Francisco Covid numbers.

On Oct. 16, DPH reports there were 50 Covid hospitalizations, or about 5.7 per 100,000 (based on an 874,000 population). DPH has not reported breakthrough hospitalizations and deaths since Sept. 17. According to the CDC, there were 39 new admissions for the seven days ending Oct. 19 (-9.30 percent from the previous seven days). For the week ending Oct. 19, covid patients accounted for 2.58 percent of hospital beds (no change from the previous week) and 5.62 percent of ICU beds (-.92 percent from the previous week).

Between Aug. 18 and Oct. 17, DPH recorded 457 new cases in Bayview Hunters Point or 121 new cases per 10,000 residents. SOMA remains the only other neighborhood with new case rates above 100 per 10,000 residents and only 4 other neighborhoods (Chinatown, Treasure Island, Tenderloin and Western Addition) have rates over 80 per 10,000 residents. All are districts in the eastern portion of San Francisco.

So far in October, White had 365 recorded infections, or 38.5 percent of October cases; Asians 230 or 24.3 percent, Latinxs 158 or 16.7 percent, Blacks 63 or 6.7 percent, Multi-racials 20 or 2.1 percent, Pacific Islanders 9 or 1 percent and Native Americans had 0 recorded infections or 0 percent of the month’s cases.

So far in October, Pacific Islanders have a 2.6 percent positivity rate, Latinxs 1.8 percent, Whites 1.6 percent, Blacks 1.6 percent, Multi-racials 1.5 percent, and Asians 1.3 percent.

Four new deaths have been recorded in October bringing the Delta total so far (August – October) to 74.

Back to the rain real quick. It felt like we had a lot of rain. However, my electronic weather station in the back shows less than 3" over the last 24 hours.

[Edge-]

https://www.independent.co.uk/news/w...-b1944954.html

FL surgeon general goes to meet lawmaker currently battling cancer, is tossed out of the office after repeatedly refusing to wear a mask.

“He just smiles and doesn’t answer. He’s very smug,” Ms Polsky told Florida Politics in an interview, adding: “And I told him several times, ‘I have this very serious medical condition.’ And he said, ‘That’s OK’, like it basically has nothing to do with what we are talking about.”

Ms Polsky further told the news blog that Dr Ladapo made an insulting comment as he left, supposedly remarking: “Sometimes I try to reason with unreasonable people for fun.” A spokesperson for the state health department denied that comment was made.

The Death Cult doesn't seem happy infecting their own unvaxxed adherents, they apparently also want to kill vaccinated people with underlying health conditions, too. "For fun".

And he's the top doctor for the state. It's Florida so I guess this should be predictable, especially given his prior comments. But this is still something else.

[Poopymonster]

https://www.independent.co.uk/news/w...-b1944954.html

FL surgeon general goes to meet lawmaker currently battling cancer, is tossed out of the office after repeatedly refusing to wear a mask.



The Death Cult doesn't seem happy infecting their own unvaxxed adherents, they apparently also want to kill vaccinated people with underlying health conditions, too. "For fun".

And he's [I]the top doctor for the state[/I]. It's Florida so I guess this should be predictable, especially given his prior comments. But this is still something else.

Apparently Suess, Banzai and Pepper weren't available to fill the role.

[Edge-]

Apparently Suess, Banzai and Pepper weren't available to fill the role.

At this point they'd all be a big step up.

Hell, I'm wondering if Doctor Strangelove might be an improvement.

[Ursus]

At this point they'd all be a big step up.

Hell, I'm wondering if Doctor Strangelove might be an improvement.

It's a shame Dr. Kevorkian isn't around anymore, he could've really helped deal with all these people with death wishes before they're able to hurt others.

[Rasulis]

We are still learning all kind of new and wonderful stuffs about the Covid virus.

Three teens with COVID-19 developed sudden severe psychiatric symptoms. Why?

Suicidal thoughts, "paranoia-like fears," delusions and "foggy brain" have been identified in three adolescents who had mild or asymptomatic COVID-19. Now, a new study into their immune responses identifies a potential mechanism by which these symptoms emerged.

The study, led by researchers at the UCSF Weill Institute for Neurosciences and the UCSF Department of Pediatrics, is the first to look at anti-neural antibodies—"turncoat" antibodies that may attack brain tissue—in pediatric patients who had been infected with SARS-CoV-2.

Over a duration of five months in 2020, a total of 18 children and teens were hospitalized with confirmed COVID at UCSF Benioff Children's Hospital San Francisco, according to the study publishing in JAMA Neurology on Oct. 25, 2021. They included the three patients in the study who underwent neurological evaluations.

The researchers examined the patients' cerebrospinal fluid, obtained via lumbar puncture, and found that two of the patients, both of whom had histories of unspecified depression and/or anxiety, had antibodies indicating that SARS-CoV-2 may have invaded the central nervous system. The same patients, who had mild/asymptomatic COVID, also had anti-neural antibodies in their cerebrospinal fluid, which were identified by immunostaining brain tissue. This suggests an immune system running amok, mistakenly targeting the brain instead of infectious microbes.

"It is way too soon to know whether COVID is a common trigger for neuropsychiatric illnesses, but it does seem to be a potent trigger for the development of autoantibodies," said co-corresponding author Samuel Pleasure, MD, Ph.D., of the UCSF Department of Neurology and of the UCSF Weill Institute. "It is currently totally unknown whether patients predisposed to neuropsychiatric illnesses are more likely to develop worsened symptoms after COVID, or whether COVID infection can act as an independent trigger."

Efforts to identify an autoantibody shared by patients with similar neuropsychiatric symptoms have so far failed, said co-first author Christopher Bartley, MD, Ph.D., of the UCSF Department of Psychiatry and of the UCSF Weill Institute. "These autoantibodies may be most clinically meaningful as markers of immune dysregulation, but we haven't found evidence that they are actually causing the patients' symptoms. There's certainly more work to be done in this area."

Unlike most psychiatric presentations, the three patients in the UCSF study had symptoms with sudden onset and rapid progression, representing a marked change from their baselines, said co-first author Claire Johns, MD, of the UCSF Department of Pediatrics. "The patients had significant neuropsychiatric manifestations despite mild respiratory symptoms, suggesting potential short and long-term effects of COVID."

After weekslong hospitalizations and ongoing psychiatric medications, the two UCSF patients, whose cerebrospinal fluid tested positive for SARS-CoV-2 antibodies and anti-neural antibodies, were treated with intravenous immunoglobulin, an immunomodulatory therapy that curbs inflammation in autoimmune disorders. Five days later, the first patient had "more organized thoughts, decreased paranoia and improved insight."

This patient was also found to have autoantibodies targeting the protein TCF4, which is genetically implicated in some cases of schizophrenia. However, "we don't know that the antibodies are actually interfering with the protein's function," said co-corresponding author, Michael R. Wilson, MD, of the UCSF Department of Neurology and of the UCSF Weill Institute, noting that the diagnosis of schizophrenia is based on a constellation of symptoms, rather than a specific biomarker.

The second patient appeared to have a modest response to immunotherapy with improved cognition and working memory, but continued to have "impaired mood and cognitive symptoms" six months later. The third patient, who had no psychiatric history and had neither SARS-CoV-2 antibodies nor anti-neural antibodies in their cerebrospinal fluid, made a complete recovery with psychiatric medications. His symptoms were ultimately attributed to recreational drug use.

A more dramatic response was reported in a case-study by Yale and UCSF, published in Biological Psychiatry, on April 9, 2021, that documented a 30-year-old patient with mildly symptomatic COVID who presented at a hospital emergency department with delusions, violent outbursts, hyper-anxiety and paranoia. After failing to achieve a lasting remission with antipsychotic medications, he was diagnosed with possible "autoimmune-mediated psychosis" and was treated with intravenous immunoglobulin. His symptoms improved after the first day of treatment and he was eventually discharged without antipsychotic medications.

"We can't say, based on such a limited number of patients, whether immunotherapy played any role in the patients' clinical course," cautioned Wilson. "In the cases of the two UCSF patients, we cannot rule out that they improved independent of immunotherapy, due either to concurrent treatment with psychiatric medications or the passage of time."

Nonetheless, the researchers agree it's unlikely that there were pre-existing autoantibodies, and they point to other disorders with psychiatric symptoms, like anti-NMDAR encephalitis syndrome, that are caused by anti-neural antibodies and respond to treatment directed at these rogue antibodies.

The researchers agree that more study is warranted, although Pleasure noted that one obstacle in expanding this research is the paucity of cerebrospinal fluid samples from pediatric patients. "We don't get to study the cerebrospinal fluid in kids very often," he said. "Children with COVID are only very rarely sick enough to warrant a lumbar puncture, and kids who are very sick with multisystem inflammatory disease usually don't have a specific reason to get one."

Meanwhile, mounting research suggests that COVID increases one's risk for psychiatric and neurological effects. A study from the United Kingdom published earlier this year found that of approximately 250,000 patients with COVID over the age of 10, the estimated incidence of a neurological or psychiatric diagnosis in the following six months was 34 percent; with 13 percent receiving their first such diagnosis.

[PACOX]

We are still learning all kind of new and wonderful stuffs about the Covid virus.

Three teens with COVID-19 developed sudden severe psychiatric symptoms. Why?

If there's one thing I learned about viruses over the past year is that apart for a handful of viruses that can actually affect the brain, our body is it's own worse enemy.

Most of the issues with COVID come from our immune system being stuck in the stone age. Why people who want to roll the dice hoping they have the right random set of genes instead of just getting the vaccine is beyond me.

[Poopymonster]

If there's one thing I learned about viruses over the past year is that apart for a handful of viruses that can actually affect the brain, our body is it's own worse enemy.

Most of the issues with COVID come from our immune system being stuck in the stone age. Why people who want to roll the dice hoping they have the right random set of genes instead of just getting the vaccine is beyond me.

It makes them feel special. They can feel like they were born being better. They believe they have superior genes. Their "pure" blood will save them, if you will.

[Khaza-R]

It makes them feel special. They can feel like they were born being better. They believe they have superior genes. Their "pure" blood will save them, if you will.

Weird take. Your entire existence is owed to superior genes prevailing over the course of hundreds of millions of years. Not to say anti-vax people suddenly taking a position of pro science when its convenient for them isn't gross, but let's also not live in the delusion that living things still around today aren't the beneficiaries of biological supremacy.

[caractacus]

Weird take. Your entire existence is owed to superior genes prevailing over the course of hundreds of millions of years. Not to say anti-vax people suddenly taking a position of pro science when its convenient for them isn't gross, but let's also not live in the delusion that living things still around today aren't the beneficiaries of biological supremacy.

That is the weird thing about this "post truth" world we now seem to be living in. People like to accept the science that is comfortable for them to believe in and dismiss the science that is uncomfortable.

[PhaelixWW]

That is the weird thing about this "post truth" world we now seem to be living in. People like to accept the science that is comfortable for them to believe in and dismiss the science that is uncomfortable.

That's exactly the problem with anti-vaxxers. They ignore the doctors who say that the vaccine is safe and effective, that it reduces the risk not just for them, but for everyone around them. Then they go to those same doctors for treatment when they get sick.

[Twdft]

Meanwhile, in the Midwest, we have concerts, and other events, concert sold out, and no huge surges after. Standard seating, no six feet between, etc.

Bring your Covid test or your vax card to get into the event, wear your mask if you want, or don't. Most don't wear one, but no one hassles anyone either way. Yanking a mask off someone there is simply not done. Someone tries that there, someone's likely to get punched in the face.

Life continues.

Bolded is probably the reason...

[msavcenko813]

How soon do you think the second wave of the pandemic will begin, and if at all?

[Rasulis]

Meanwhile, in the Midwest, we have concerts, and other events, concert sold out, and no huge surges after. Standard seating, no six feet between, etc.

Bring your Covid test or your vax card to get into the event, wear your mask if you want, or don't. Most don't wear one, but no one hassles anyone either way. Yanking a mask off someone there is simply not done. Someone tries that there, someone's likely to get punched in the face.

Life continues.

No mask mandate for outdoor concert. Although full vaccination or clean test result are required.

Mask mandate plus full vaccination or clean test results for indoor concert.

We were at the Eagles' concert at Chase Center Saturday, and everybody were masked. We were sitting in the nosebleed section and it was packed. No six feet separation.