As a Michigan fan I would say Michigan has the formula and tools to beat OSU again but it doesn't guarantee anything. Michigan hasn't won in Columbus since Bill Clinton was president.
The biggest hole in Michigan's defense seems to be defending 50/50 jump balls, the DBs almost always lose them against meh teams so I'm certainly not sold on the idea Michigan beating OSU is a sure thing with their WR corp. Now if some rain dancer can come and summon a gnarly storm for the game then OSU is screwed but in perfect weather I think this game is complete tossup.