Perhaps Diablo games are not for you, then? That's what these games ARE. It's like saying "my fear is that tennis will be all about hitting yellow balls with a racket, which I think is an enormous waste of time" - cool, don't play tennis, then. Easy solution.
Not on the core formula, no. That's what defines a genre. It'd be like Counterstrike "innovating" on shooting people with guns and throwing bombs - that's... what that kind of game is. If you want something else, play a different kind of game. That's why we HAVE genres, so you know what's what from the label.
That being said, they are innovating on other stuff, like the whole MMO vibe. That's different from previous Diablo titles.