Over the last 2 weeks of playing, I've occasionally ran into an issue where my computer will simply shut off and reboot itself when certain things happen in the game. It usually happens when I'm zoomed in (downed state) with several ground-targeted spells colliding on the screen, but I just recently also had it happen while I was swimming next to a waterfall.
I discovered this after the first reboot happening as soon as I fell into the water at the base of the falls and then again while I was dealing with the zombie that jumped on me as I logged back in. To prevent a third time, I turned all of my graphics from the complete maximum to the complete minimum before entering the game. I then stood under the waterfall and turned up one setting at a time, pausing for several seconds between each one. Everything was working just fine until I clicked Medium on Shaders - it was nearly an instant reboot. I then tested High while standing further away, and it happened a bit later than the previous. I was even watching my GPU usage (was @ 30%) and temperatures (were in the mid 60s) to see if anything was abnormal.
So, I can run the game completely fine with everything maxed anywhere, except in a few specific places. Otherwise, I can have Shaders on Low and avoid the issue altogether. I have absolutely no clue what's causing this.
I'm using an Intel Core i5-3570k, 3.4 GHz processor and a Nvidia GeForce GTX 570 with the 306.02 Beta driver.