I've only used 7-9 G-Keys specifically for my defensive CD's and I'm familiarizing myself with them very quickly, since I'm a Death Knight that would be AMS, IB, Ghoul Heal, Remorseless and Death's Embrace, my main abilities I use my mouse for since I have a Naga, I'm trying to get used to the side-buttons on my mouse for my main abilities, but don't get me wrong keybinds are great and I use them myself, 2 for interrupts and another 2 for Death Grip and Chain's of Ice, I just don't want to make it difficult on my remembering of patterns and I've found this way to be easier for me, I tried keybinding but I just couldn't get past more than three modifiers.
I'm aware G-Keys may not be the usual bindings, but they're working for me
I'm not a heavy PvP'er so all sorts of Macros are not likely to be made for me. Hey, if it's a difficult way then so be it, sometimes difficult things are more suitable for some than the proper ways that are easier! What matters is I'm shifting from clicking after 7 years of WoW
Thanks for the tips and pointers though.