I'm not really interested in any. I haven't enjoyed any of the Civilization games that came after Civilization 3, but I might give the upcoming one a chance. I spent a ridiculous amount of time playing Civ3 back in the day, but Civ4/Civ5 just didn't do it for me. I can't explain why.
I am somewhat interested in Shadow of Mordor. Might give it a shot if it ever goes for some really low cost during a Steam sale.
My most anticipated games are still a while from getting here. Mortal Kombat X (if it comes out on PC), Killing Floor 2, Trine 3 (if it ever becomes more than just a "We hope to revisit Trine at some point in the future" line), and the next Starcraft 2 expansion are my biggest ones. Those games won't be coming out this year.