Having the Dragon capable of being either gender changes the story. There's important reasons all the Aes Sedai are female. There's important reasons the Reds hunt down and gentle any man caught channeling the One Power. Also to note, they had some of the most powerful Aes Sedai locking weaves around Logan, a self taught male, who's only been channeling the One Power for a handful of years, where you needed multiple of these very powerful Aes Sedai to hold the weave, and it was taking everything they had. Saidin and saidar are different and it's pretty important point and reason that the Dragon uses Saidin.
That said, I think they are just messing with us. I suspect Rand will still be the dragon. The other differences feel more cosmetic, so they don't bother me so much. Overall I have enjoyed the series so far.
I suppose one thing that sticks in the back of my head, that I can overlook, but takes me out of the immersion is the way the show runners handled diversity in the series. There's plenty of diversity in the books, but it's not within every town. In the books, every area is mostly ethnically homogeneous, to the point that people have a good idea where you came from by how you look. So far in the series, every town looks like a mini-sampling of America's big city diversity, to the point that you would have no idea where anyone comes from based on how they look.
For example, I don't have a problem at all with the casting choices of Lan, Moraine, and Egwene, as they all come from different regions, so their diversity from each other makes sense. But in the show when you look at Mat, Egwene, Nynaeve, and Perrin; they also look like they all come from different regions which doesn't feel right. And their differences makes Rand not stand out so much, like he does in the books, where folks note that it does not looks like Rand belongs in the Two Rivers region.
Anyway, that's more of a minor complaint, I can look past it, just takes me out of the immersion of the show sometimes.
...oh yeah, and in the books the Aes Sedai have ageless appearances, which did not make it to the show. So again cosmetic, doesn't really change the story at all, just another thing that regularly pops in my head while watching the show.