Just to illustrate the point, a very basic skill that is nevertheless critical to nearly all fights : getting out of fire (and conversely not getting in), or more generally positioning. It can just as much NOT pressing key than pressing them, the core component being to simply be placed at the right time at the right place.
More generally, all the situational awareness and decision-making is mostly unrelated to key press.
To be a bit simplistic, going into a bad place and running back to kill the add that spawned require more key presses in a shorter time than just not moving from the adequate place and being able to switch immediately to the add, yet it's actually playing better.