Originally Posted by
FuxieDK
At BlizzCon, they said, at the end of each level, you got a choice of 2 or 3 buffs, you'd have for the rest of the run.
If your RNG is bad and you always get e.g. single target buffs, but the dungeon only throws big packs at you, you lack the AoE buffs. As you progress the packs gets harder and harder, but you don't get any buff to combat it (because you got single target buff or stealth detection or treasure find etc), and you will fail at level 4.... Had you gotten the right buffs, you might go to level 15.