I'll name three because they are known in different fields.
Luis von Ahn. Founder of Duolingo and co-founder of Captcha and Recaptcha (Those annoying words and pictures you have to type and click to verify you aren't a robot)
Miguel Angel Asturias (Nobel Prize in Literature)
Regarding actors, celebrities and artists. Then probably Oscar Isaac (recently known for playing Poe in the last 3 Star Wars films)