We cannot really survive in space though. Reproduction in space is most likely not possible, or at least severely impacted, and we have to wear suits so that we don't boil and freeze at the same time when exposed to outer space directly.
But you're right when you say that the same laws of physics apply to us and them.
However, think of it as you trying to commnunicate with a shark. You know the shark can feel blood from miles away. A shark would still be forever unable to explain to you how he does it.
Maybe if the alien race was advanced enough to establish a common communication with us and we're not talking about only an animal-type alien, then we could better understand each other. The problem is still the old saying, that any sufficiently advanced technology is indistinguishable from magic.
Though my hopes are slim anyway. Whatever Webb finds, it will be millions opon millions of years old. If there WAS some signature of life out there, there is no way to bring forth definitive proof that there is still something out there.