I believe it, see no reason not too. And I don't contest the idea of pinhead being female. However I do understand people's concerns. Because lately we see a lot of swapping of any kind really and often it becomes the focus and then the show is bad because of that focus.
So even if it's canon I understand the concern where it comes from. If the "change" is made for authentic reasons it will probably turn out well. But even if it is canon it isn't necessarily the reason to change it for whoever is running the show, they might have other reasons, then it'll probably turn out bad because priorities are somewhere else.