Completely depends on your play style and glyph setup.
Blood is really nice for the RP gen (Butchery), more AP (Bladed Armor) and increase to 2H wep dmg and Crit.
Frost is really nice for inc to Frost dmg (Black Ice) and thats about all from the top of that tree other than having a larger RP poll available.
tbh for an UH build something like
http://talent.mmo-champion.com/?deat...5&version=9767 will prolly be close to top dmg. Again I made this spec in 15 seconds so please dont pull the Theiry crafting its the point of UH / Blood being better than UH / Frost im making.