Just struggle for a while and it will come naturally, trust me. Accommodating to key bindings after being a clicker or accommodating to completely new key bindings is a pain for a while but always turns out for the better. It's not a good idea to get a relapse and wanting to unbind spells because you can't remember them fast enough. Just make sure your keybinds are visible until you're used to it.
As for your second question: get a mouse with extra buttons. This is the best advice I can give you peripherals across the board. Once you get one you'll never be able to play without it. I also unbound the targetnearestenemytarget function off of tab and bound spells there, it allows for 3 more keybinds with alt and shift modifiers, the original tab function isn't all that fantastic when it cuts to the chase, you'll want more accuracy in what you target than that.
---------- Post added 2011-01-31 at 10:08 PM ----------
Fixed that for ya.