I know a lot of people say, like it's obvious, "Click!" or "Tab!" For me, both present problems; it can take a few seconds to locate the right place to click for the head, which is seconds lost not DPSing. And I'm a female player and I've found tabbing to be harder than people assume it is. After thinking about it, I think it's because my hands are small. I have to extend my pinkie pretty much to its max to hit tab, and my pinkie isn't all that strong, so the tabbing isn't smooth since the key is bigger than the "normal" letter keys and takes more effort to push down. If I had huge hands with strength and reach it would be a non-issue I suspect, like it is for most of you. But for a female or a younger male player they might have issues just due to hand size.