This.
Al'akir fits #4 very well. In 25 you have very limited room to move in p1 to avoid the tornadoes (not that it's hard). In 10 you can spread out and have a whole lot more room to maneuver around the random crap that happens. The Ascendant Council is another example of this. In 10 man you have fewer people eating the lighting discharge thing while in 25 you have multiple people chaining it.
Atramedes is a good example of #2. In 10 I'm pretty sure with only 4-5 people alive you're gonna end up hitting the soft enrage (Zero gongs left) if everyone died early on. In 25 he can easily be 10-14manned for a good 50-60% of the fight (Yes i know that's absolutely horrible).
It will hurt your raid a lot more trying to carry a few sub par players in 10man than 25 also.
This is all regular to. Haven't started up heroics yet.