Aside from the really obvious stuff like diseases, war, etc....
- Piece of shit cars that spew out huge noxious clouds/fumes that everyone within a mile behind them can smell.
- Assholes who leave their shopping carts in the middle of grocery store parking lots so they can roll off and hit someone's car later.
- Bad drivers (I could list about 10 different examples, but I'm just gonna leave it at that).
- Unreasonably low 40mph speed limits on 1-mile+ stretches of straight road where nothing dangerous is going to happen.
- Speeding tickets that you get when said areas (see above) are used to set up speed traps.
- Top 40 "music" here.
- Government and politics.
- Unreasonable taxation.
- Animal cruelty. When I hear these stories about how a group of teenagers thought it'd be funny to set a cat on fire, it makes my blood boil.
- Gas prices.
- Political correctness.
- Celebrity "news" on TV and various other places. I don't care that some famous celebrity was spotted taking a dump 10 minutes ago.
- Nancy Grace.
- People who claim racism because they didn't get their way.
- Online grammar Nazis. Particularly the ones who think everyone on Earth is supposed to speak 100% perfect English.
- "Reality" TV.
- Elitists in online games. I'm looking at the ones in games like WoW who go "LOL STUPID NOOB CASUALS QUIT TEH GAME NOW"
- Bad sportsmanship in online games. "LOL GG NOOB U LOST GO KILL URSELF" when you lose and "FUK U RETARD U CHEATED" when you win.
- My work cell phone when it rings on my days off.
- Mornings.
- Hearing some untalented celebrity butcher the National Anthem before every major sports event.
- People who blame school shootings on violence in video games.
- People who hate on others for having religious beliefs. I respect your beliefs, so you should respect mine.
- People who insist on turning what should be a 15-second phone call into 10 minutes of texting back and forth.
- Restaurants that act like I just asked for the most complicated thing in the world when I ask for a sandwich without the mayonnaise.
- People who say "I could care less" when they really mean "I couldn't care less" about something.
- People who smoke weed and won't shut up about the fact that they smoke weed. I have no problems with people who smoke weed because that's your own business, but please shut up with the "LOL I GOT SOOOOOOOOOOO BAKED LAST NIGHT MAN LOL" stuff.
- Chicks who walk around in slutty outfits and expect guys not to look. If you're gonna stick 'em in my face, I'm gonna look at 'em. Deal with it.
- Annoying and/or gross commercials on TV. I don't want to see a commercial about "OMFG CURE YOUR UGLY TOENAIL FUNGUS NOW!!11!" or "LOL LOOKS LIKE TEH MUCUS IS MOVIN' IN!!!111!!" when I'm trying to eat.